Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR1E | P28566 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28501579 | 0.81 | TDP1 (0.40) | ALDH1A1HTTHTR1AADRA2AADRA2B | |
| SCHEMBL292913 | 0.78 | METAP1 (0.36) | ALDH1A1ADRA2AADRA2BADRA2CHTR2A | |
| SCHEMBL28691266 | 0.74 | KMT2A (0.47) | ALDH1A1METAP1MEN1KMT2AHPGD | |
| SCHEMBL3430076 | 0.74 | METAP1 (0.40) | ALDH1A1HTR1DHTR2AHTR2CHTR6 | |
| SCHEMBL13978037 | 0.74 | METAP1 (0.36) | ALDH1A1HTR2AMETAP1MEN1KMT2A | |
| SCHEMBL3028098 | 0.71 | METAP1 (0.40) | ALDH1A1HTR1DHTR2AHTR2CHTR6 | |
| SCHEMBL13376478 | 0.71 | HTR2A (0.47) | ALDH1A1HTR1DHTR2AHTR2CSLC6A4 | |
| SCHEMBL22129621 | 0.69 | ALDH1A1 (0.35) | ALDH1A1HTTLMNAHTR1AADRA2A | |
| SCHEMBL23421392 | 0.69 | HTR2A (0.40) | HTR1AADRA2ASLC6A2HTR1DHTR2A | |
| SCHEMBL4367677 | 0.68 | TDP1 (0.50) | ALDH1A1LMNASLC6A2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101098631-A | Modified proteins with altered aggregation properties | CSM NEDERLAND BV (NL) | 2008-01-02 | — | — | CN | disclosed |