Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | AHR | P35869 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28691266 | 0.87 | KMT2A (0.47) | MEN1KMT2AALDH1A1METAP1 | |
| SCHEMBL13978037 | 0.82 | METAP1 (0.36) | TDP1AHRMEN1KMT2ACYP3A4 | |
| SCHEMBL13977730 | 0.82 | METAP1 (0.36) | TDP1AHRMEN1KMT2ACYP3A4 | |
| SCHEMBL3875462 | 0.82 | GPR84 (0.36) | TDP1AHRMEN1KMT2ACYP3A4 | |
| SCHEMBL292913 | 0.82 | METAP1 (0.36) | TDP1AHRMEN1KMT2ACYP3A4 | |
| SCHEMBL27696265 | 0.81 | ALDH1A1 (0.37) | TDP1AHRMEN1KMT2ACYP3A4 | |
| SCHEMBL13376478 | 0.79 | HTR2A (0.47) | CYP3A4MAPTHSD17B10ALDH1A1CYP2A6 | |
| SCHEMBL3430076 | 0.79 | METAP1 (0.40) | TDP1AHRMEN1KMT2ACYP3A4 | |
| SCHEMBL3028098 | 0.79 | METAP1 (0.40) | TDP1AHRMEN1KMT2ACYP3A4 | |
| SCHEMBL23421392 | 0.77 | HTR2A (0.40) | MEN1KMT2AMAPTGPR84METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111960987-B | Synthesis method of methylene bis (isoindole) compound | 温州大学 | 2022-02-11 | — | — | CN | claimed |
| CN-111960987-A | Synthesis method of methylene bis (isoindole) compound | 温州大学 | 2020-11-20 | — | — | CN | claimed |
| CN-111960987-B | Synthesis method of methylene bis (isoindole) compound | 温州大学 | 2022-02-11 | — | — | CN | disclosed |
| CN-111960987-B | Synthesis method of methylene bis (isoindole) compound | 温州大学 | 2022-02-11 | — | — | CN | disclosed |
| CN-111960987-B | Synthesis method of methylene bis (isoindole) compound | 温州大学 | 2022-02-11 | — | — | CN | disclosed |
| CN-111960987-A | Synthesis method of methylene bis (isoindole) compound | 温州大学 | 2020-11-20 | — | — | CN | disclosed |