Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28501579 | 0.87 | TDP1 (0.40) | KMT2AMEN1ALDH1A1METAP1 | |
| SCHEMBL13978037 | 0.75 | METAP1 (0.36) | KMT2AMEN1ALDH1A1HPGDMETAP1 | |
| SCHEMBL292913 | 0.75 | METAP1 (0.36) | KMT2AMEN1ALDH1A1HPGDMETAP1 | |
| SCHEMBL27696265 | 0.74 | ALDH1A1 (0.37) | KMT2AMEN1ALDH1A1HPGDMETAP1 | |
| SCHEMBL4367677 | 0.73 | TDP1 (0.50) | KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL3430076 | 0.72 | METAP1 (0.40) | KMT2AMEN1ALDH1A1METAP1TAAR1 | |
| SCHEMBL3028098 | 0.72 | METAP1 (0.40) | KMT2AMEN1ALDH1A1METAP1TAAR1 | |
| SCHEMBL13376478 | 0.72 | HTR2A (0.47) | ALDH1A1METAP1TAAR1 | |
| SCHEMBL23421392 | 0.71 | HTR2A (0.40) | KMT2AMEN1ELANEMETAP1 | |
| SCHEMBL28820480 | 0.71 | ALDH1A1 (0.51) | KMT2AMEN1LTB4RELANEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114075130-A | Benzoazaheterocycle compound and preparation method thereof | 复旦大学 | 2022-02-22 | — | — | CN | claimed |
| CN-114075130-B | Benzazepine compounds and preparation method thereof | 复旦大学 | 2023-05-09 | — | — | CN | disclosed |
| CN-114075130-B | Benzazepine compounds and preparation method thereof | 复旦大学 | 2023-05-09 | — | — | CN | disclosed |
| CN-114075130-A | Benzoazaheterocycle compound and preparation method thereof | 复旦大学 | 2022-02-22 | — | — | CN | disclosed |
| CN-114075130-A | Benzoazaheterocycle compound and preparation method thereof | 复旦大学 | 2022-02-22 | — | — | CN | disclosed |