SCHEMBL27696972

SCHEMBL27696972

O=C(Nc1cc(C=Cc2ccccc2)ccc1C(=O)O)c1ccc(F)c(F)c1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.49
HDAC8 Q9BY41 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
SNCA P37840 2/20 0.48
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
PKM P14618 2/20 0.47
GRIK1 P39086 2/20 0.46
MAPT P10636 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
KCNK2 O95069 1/20 0.46
KCNK10 P57789 1/20 0.46
ACLY P53396 2/20 0.45
PRSS12 P56730 1/20 0.45
PTPN1 P18031 2/20 0.45
HNF4A P41235 1/20 0.45
PIM1 P11309 1/20 0.45
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27716652 0.88 SNCA (0.63) HDAC1SNCAMEN1KMT2APKM
SCHEMBL2276655 0.86 PKM (0.62) HDAC1SNCAMEN1KMT2APKM
SCHEMBL2276651 0.86 PKM (0.62) HDAC1SNCAMEN1KMT2APKM
SCHEMBL27696878 0.85 SNCA (0.57) HDAC1HDAC6SNCAMEN1KMT2A
SCHEMBL27716729 0.85 SNCA (0.53) HDAC1SNCAMEN1KMT2APKM
SCHEMBL27696790 0.85 KCNK2 (0.56) HDAC1MEN1KMT2APKMGRIK1
SCHEMBL28943766 0.84 L3MBTL1 (0.50) SNCAMEN1KMT2AGRIK1TDP1
SCHEMBL2276923 0.84 SNCA (0.66) HDAC1SNCAMEN1KMT2APKM
SCHEMBL2276918 0.84 SNCA (0.66) HDAC1SNCAMEN1KMT2APKM
SCHEMBL27696984 0.83 SLC16A3 (0.53) HDAC1HDAC8HDAC6MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101094829-A Novel anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO LTD (JP) 2007-12-26 CN disclosed