SCHEMBL27716652

SCHEMBL27716652

O=C(Nc1cc(C=Cc2ccccc2)ccc1C(=O)O)c1ccc(F)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 2/20 0.63
TRPA1 O75762 1/20 0.54
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
MAPT P10636 1/20 0.51
PKM P14618 1/20 0.51
GRIK1 P39086 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
KCNK2 O95069 4/20 0.50
HDAC1 Q13547 2/20 0.50
BCL2L1 Q07817 1/20 0.49
BAD Q92934 1/20 0.49
PTPN1 P18031 1/20 0.49
KCNK10 P57789 3/20 0.48
KCNK3 O14649 1/20 0.48
KCNK9 Q9NPC2 1/20 0.48
DHODH Q02127 1/20 0.48
RAB9A P51151 2/20 0.47
CYP2D6 P10635 2/20 0.47
KDM4E B2RXH2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2276923 0.96 SNCA (0.66) SNCATRPA1MEN1KMT2AMAPT
SCHEMBL2276918 0.96 SNCA (0.66) SNCATRPA1MEN1KMT2AMAPT
SCHEMBL2276655 0.91 PKM (0.62) SNCAMEN1KMT2AMAPTPKM
SCHEMBL2276651 0.91 PKM (0.62) SNCAMEN1KMT2AMAPTPKM
SCHEMBL27716729 0.90 SNCA (0.53) SNCATRPA1MEN1KMT2AMAPT
SCHEMBL27716751 0.88 TRPA1 (0.58) SNCATRPA1MEN1KMT2AMAPT
SCHEMBL27696878 0.88 SNCA (0.57) SNCATRPA1MEN1KMT2AMAPT
SCHEMBL27696972 0.88 HDAC1 (0.49) SNCAMEN1KMT2AMAPTPKM
SCHEMBL2272567 0.87 KMT2A (0.55) SNCATRPA1MEN1KMT2AMAPT
SCHEMBL2272560 0.87 KMT2A (0.55) SNCATRPA1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101094829-A Novel anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO LTD (JP) 2007-12-26 CN disclosed