Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19356111 | 0.83 | CHRNB2 (0.33) | THRBCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL19356112 | 0.82 | THRB (0.31) | THRB | |
| SCHEMBL967292 | 0.78 | PGR (0.31) | — | |
| SCHEMBL15011877 | 0.74 | KMT2A (0.54) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL20186794 | 0.74 | GABRR1 (0.33) | — | |
| SCHEMBL20186756 | 0.74 | GABRR1 (0.33) | — | |
| SCHEMBL15016144 | 0.74 | — | — | |
| SCHEMBL16741679 | 0.74 | CHRNB2 (0.35) | THRBCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL20186754 | 0.74 | GABRR1 (0.33) | — | |
| SCHEMBL19814582 | 0.74 | CHRNB2 (0.35) | THRBCHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249088-A1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249088-A1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | TRPV1, FGFR3, GPR17 | THRB 1145/4885CHRNB2 871/4885CHRNB4 1181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.