Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.56 |
| ▸ | SLC5A2 | P31639 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CBS | P35520 | 1/20 | 0.50 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145265 | 0.85 | LMNA (0.78) | MAPTHPGDMEN1KMT2ACYP3A4 | |
| SCHEMBL6396398 | 0.85 | LMNA (0.49) | MAPTHPGDMEN1KMT2ACYP3A4 | |
| SCHEMBL8578359 | 0.85 | MAPT (0.55) | MAPTHPGDMEN1KMT2ACYP3A4 | |
| SCHEMBL8575394 | 0.85 | MAPT (0.69) | MAPTHPGDMEN1KMT2ACYP3A4 | |
| SCHEMBL30913242 | 0.83 | SLC5A1 (0.76) | MAPTHPGDMEN1KMT2ACYP3A4 | |
| SCHEMBL19668159 | 0.83 | SLC5A1 (0.76) | MAPTHPGDMEN1KMT2ACYP3A4 | |
| SCHEMBL6395053 | 0.82 | MAPT (0.47) | MAPTHPGDMEN1KMT2ACYP3A4 | |
| SCHEMBL6396393 | 0.82 | LMNA (0.46) | MAPTHPGDMEN1KMT2ACYP3A4 | |
| SCHEMBL14855982 | 0.81 | ESR1 (0.72) | MAPTHPGDMEN1KMT2ACYP3A4 | |
| SCHEMBL24841623 | 0.80 | CYP19A1 (0.70) | MAPTHPGDMEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101146766-A | Acyl hydrazides as kinase inhibitors, in particular for SGK | MERCK PATENT GMBH (DE) | 2008-03-19 | — | — | CN | disclosed |