SCHEMBL27697262

SCHEMBL27697262

O=C(O)COC(=O)CCCCCCC(=O)OCC(=O)O

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAM P19021 3/20 0.79
DGKA P23743 1/20 0.48
TSHR P16473 5/20 0.48
LMNA P02545 3/20 0.48
NFKB1 P19838 1/20 0.48
PMP22 Q01453 1/20 0.48
MAPT P10636 1/20 0.41
GPR84 Q9NQS5 3/20 0.40
FFAR1 O14842 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
ALDH1A1 P00352 3/20 0.39
DNM1 Q05193 1/20 0.39
PPARG P37231 3/20 0.39
PPARD Q03181 3/20 0.39
PPARA Q07869 3/20 0.39
HDAC11 Q96DB2 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
SLC22A6 Q4U2R8 1/20 0.39
SLC22A8 Q8TCC7 1/20 0.39
TLR2 O60603 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1845790 1.00 PAM (0.79) PAMDGKATSHRLMNANFKB1
SCHEMBL27714306 1.00 PAM (0.79) PAMDGKATSHRLMNANFKB1
SCHEMBL1845834 0.97 PAM (0.75) PAMDGKATSHRLMNANFKB1
SCHEMBL1712357 0.95 PAM (0.73) PAMTSHRLMNANFKB1PMP22
SCHEMBL27730313 0.95 PAM (0.73) PAMTSHRLMNANFKB1PMP22
SCHEMBL10578392 0.92 PAM (0.69) PAMTSHRLMNANFKB1PMP22
SCHEMBL11956805 0.92 PAM (0.69) PAMDGKATSHRLMNANFKB1
SCHEMBL8671140 0.89 PAM (1.00) PAMDGKATSHRMAPTGPR84
SCHEMBL10555970 0.89 PAM (1.00) PAMDGKATSHRMAPTGPR84
SCHEMBL11354026 0.89 PAM (1.00) PAMDGKATSHRMAPTGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103534101-A Epoxidised elastomer compositions modified by silanes DOW CORNING 2014-01-22 CN disclosed
CN-101146868-B Organosiloxane compositions DOW CORNING 2013-04-24 CN disclosed
CN-101146856-B Organosiloxane compositions DOW CORNING 2012-12-05 CN disclosed
CN-101405345-B Organosiloxane compositions DOW CORNING 2012-07-04 CN disclosed
CN-101151325-B Organosiloxane compositions DOW CORNING INC 2012-04-11 CN disclosed
CN-101405345-A Organosiloxane compositions DOW CORNING (US) 2009-04-08 CN disclosed
CN-101400516-A impregnated flexible sheet DOW CORNING (US) 2009-04-01 CN disclosed
CN-101151325-A Organosiloxane compositions DOW CORNING (US) 2008-03-26 CN disclosed
CN-101146856-A Organosiloxane compositions DOW CORNING (US) 2008-03-19 CN disclosed
CN-101146868-A Organosiloxane compositions DOW CORNING (US) 2008-03-19 CN disclosed