SCHEMBL1845834

SCHEMBL1845834

O=C(O)COC(=O)CCCCC(=O)OCC(=O)O

nearest known ligand 0.75

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PAM P19021 3/20 0.75
LMNA P02545 3/20 0.45
DGKA P23743 1/20 0.44
TSHR P16473 6/20 0.43
NFKB1 P19838 1/20 0.43
PMP22 Q01453 1/20 0.43
CYP1A2 P05177 1/20 0.39
CTH P32929 1/20 0.39
CBS P35520 1/20 0.39
THPO P40225 1/20 0.39
SLC22A6 Q4U2R8 1/20 0.38
THRB P10828 1/20 0.38
MAPT P10636 1/20 0.38
DNM1 Q05193 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
ATM Q13315 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27714306 0.97 PAM (0.79) PAMLMNADGKATSHRNFKB1
SCHEMBL1845790 0.97 PAM (0.79) PAMLMNADGKATSHRNFKB1
SCHEMBL27697262 0.97 PAM (0.79) PAMLMNADGKATSHRNFKB1
SCHEMBL11956805 0.95 PAM (0.69) PAMLMNADGKATSHRNFKB1
SCHEMBL10578392 0.95 PAM (0.69) PAMLMNATSHRNFKB1PMP22
SCHEMBL27730313 0.93 PAM (0.73) PAMLMNATSHRNFKB1PMP22
SCHEMBL1712357 0.93 PAM (0.73) PAMLMNATSHRNFKB1PMP22
SCHEMBL585970 0.90 PAM (0.63) PAMLMNATSHRNFKB1PMP22
SCHEMBL9239007 0.89 PAM (0.96) PAMDGKATSHRSLC22A6MAPT
SCHEMBL11282889 0.89 PAM (0.62) PAMLMNADGKATSHRNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160023998-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL LLC (US) 2016-01-28 US disclosed
US-20160023998-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL LLC (US) 2016-01-28 US disclosed
US-9174924-B2 Hydrolysable linkers and cross-linkers for absorbable polymers BEZWADA BIOMEDICAL, LLC (US) 2015-11-03 US disclosed
US-9174924-B2 Hydrolysable linkers and cross-linkers for absorbable polymers BEZWADA BIOMEDICAL, LLC (US) 2015-11-03 US disclosed
US-20150259275-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL LLC (US) 2015-09-17 US disclosed
US-20150259275-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL LLC (US) 2015-09-17 US disclosed
US-9045396-B2 Hydrolysable linkers and cross-linkers for absorbable polymers BEZWADA BIOMEDICAL, LLC (US) 2015-06-02 US disclosed
US-9045396-B2 Hydrolysable linkers and cross-linkers for absorbable polymers BEZWADA BIOMEDICAL, LLC (US) 2015-06-02 US disclosed
US-20140163253-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL, LLC (US) 2014-06-12 US disclosed
US-20140163253-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL, LLC (US) 2014-06-12 US disclosed
WO-2010019716-A1 AABB-POLY(DEPSIPEPTIDE) BIODEGRADABLE POLYMERS AND METHODS OF USE MEDIVAS, LLC (US) 2010-02-18 WO disclosed
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF BEZWADA BIOMEDICAL, LLC (US) 2009-11-19 US disclosed
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF BEZWADA BIOMEDICAL, LLC (US) 2009-11-19 US disclosed
US-20090082540-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL, LLC (US) 2009-03-26 US disclosed
US-20090082540-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS BEZWADA BIOMEDICAL, LLC (US) 2009-03-26 US disclosed
CN-101027319-A Heparin binding peptide ENKAM PHARMACEUTICALS AS (DK) 2007-08-29 CN disclosed
CN-101027320-A FGFR binding peptides ENKAM PHARMACEUTICALS AS (DK) 2007-08-29 CN disclosed
CN-1863820-A Compounds comprising lpa ENKAM PHARMACEUTICALS AS (DK) 2006-11-15 CN disclosed
EP-0300601-A2 Process for the production of sintered aluminium nitrides KERAMONT ADVANCED CERAMIC PRODUCTS CORPORATION (US) 1989-01-25 EP disclosed
US-4778778-A ADDING HYDROGEN/INERT GAS MIXTURE DURING SINTERING CYCLE KERAMONT ADVANCED CERAMIC PRODUCTS CORPORATION (US) 1988-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150259275-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS SI, KDM8, APEH PAM 22/4885LMNA 2710/4885DGKA 1239/4885
US-20090082540-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS SI, KDM8, APEH PAM 22/4885LMNA 2710/4885DGKA 1239/4885
US-20160023998-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS SI, KDM8, APEH PAM 22/4885LMNA 2710/4885DGKA 1239/4885
US-20090285896-A1 BIOABSORBABLE POLYESTERAMIDES AND USES THEREOF PAICS, UROD, PUF60 PAM 22/4885LMNA 1572/4885DGKA 926/4885
US-20140163253-A1 HYDROLYSABLE LINKERS AND CROSS-LINKERS FOR ABSORBABLE POLYMERS SI, KDM8, APEH PAM 22/4885LMNA 2710/4885DGKA 1239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.