Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAM | P19021 | 3/20 | 0.79 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARD | Q03181 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27697262 | 1.00 | PAM (0.79) | PAMDGKATSHRLMNANFKB1 | |
| SCHEMBL27714306 | 1.00 | PAM (0.79) | PAMDGKATSHRLMNANFKB1 | |
| SCHEMBL1845834 | 0.97 | PAM (0.75) | PAMDGKATSHRLMNANFKB1 | |
| SCHEMBL27730313 | 0.95 | PAM (0.73) | PAMTSHRLMNANFKB1PMP22 | |
| SCHEMBL1712357 | 0.95 | PAM (0.73) | PAMTSHRLMNANFKB1PMP22 | |
| SCHEMBL10578392 | 0.92 | PAM (0.69) | PAMTSHRLMNANFKB1PMP22 | |
| SCHEMBL11956805 | 0.92 | PAM (0.69) | PAMDGKATSHRLMNANFKB1 | |
| SCHEMBL11047565 | 0.89 | PAM (1.00) | PAMDGKATSHRMAPTGPR84 | |
| SCHEMBL4725841 | 0.89 | PAM (1.00) | PAMDGKATSHRMAPTGPR84 | |
| SCHEMBL7775439 | 0.89 | PAM (1.00) | PAMDGKATSHRMAPTGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323671-A1 | AABB-POLY(DEPSIPEPTIDE) BIODEGRADABLE POLYMERS AND METHODS OF USE | Medivas, LLC (US) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010019716-A1 | AABB-POLY(DEPSIPEPTIDE) BIODEGRADABLE POLYMERS AND METHODS OF USE | MEDIVAS, LLC (US) | 2010-02-18 | — | — | WO | disclosed |
| US-20100040664-A1 | AABB-POLY(DEPSIPEPTIDE) BIODEGRADABLE POLYMERS AND METHODS OF USE | MEDIVAS, LLC (US) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100040664-A1 | AABB-POLY(DEPSIPEPTIDE) BIODEGRADABLE POLYMERS AND METHODS OF USE | DNPEP, NPEPPS, APEH | PAM 20/4885DGKA 1105/4885TSHR 4474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.