Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 2/20 | 0.31 |
| ▸ | ARG1 | P05089 | 3/20 | 0.31 |
| ▸ | ARG2 | P78540 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29078894 | 0.88 | GNAI3 (0.32) | MEN1KMT2AGNAI3GNAO1GNAI1 | |
| SCHEMBL8404679 | 0.77 | CYP2C19 (0.37) | ARG1ARG2CYP2C19 | |
| SCHEMBL7401320 | 0.77 | CYP2C19 (0.37) | ARG1ARG2CYP2C19 | |
| SCHEMBL27730665 | 0.72 | CYP2C19 (0.33) | ARG1ARG2CYP2C19 | |
| SCHEMBL1841513 | 0.70 | ALDH1A1 (0.42) | MEN1KMT2APOLBALDH1A1CYP2C19 | |
| SCHEMBL3704761 | 0.69 | CYP2C19 (0.35) | CYP2C19 | |
| SCHEMBL28320630 | 0.69 | MAPT (0.33) | MAPTNAAAARG1 | |
| SCHEMBL14322639 | 0.68 | CES1 (0.37) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL28394620 | 0.68 | NAAA (0.40) | MEN1KMT2AALDH1A1NAAA | |
| SCHEMBL1041620 | 0.68 | NAAA (0.43) | MEN1KMT2AGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113933414-A | Method for detecting organic impurities in irbesartan amlodipine besylate composite preparation | 株洲千金药业股份有限公司 | 2022-01-14 | — | — | CN | disclosed |
| CN-101155803-A | Method for obtaining a pharmaceutically active compound (irbesartan) and its synthesis intermediate | INKE SA (ES) | 2008-04-02 | — | — | CN | disclosed |