Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 18/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.58 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.52 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.52 |
| ▸ | MLNR | O43193 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27985246 | 0.90 | CACNA1C (0.49) | FFAR4FFAR1CACNA1CSCN5AMLNR | |
| SCHEMBL28857157 | 0.86 | ITGB3 (0.54) | FFAR4FFAR1CACNA1CSCN5AMLNR | |
| SCHEMBL28857113 | 0.86 | ITGB3 (0.54) | FFAR4FFAR1CACNA1CSCN5AMLNR | |
| SCHEMBL27755780 | 0.86 | ITGB3 (0.54) | FFAR4FFAR1CACNA1CSCN5AMLNR | |
| SCHEMBL6856918 | 0.83 | HTR1A (0.52) | FFAR4FFAR1CACNA1CSCN5AMLNR | |
| SCHEMBL14681243 | 0.83 | HTR1A (0.52) | FFAR4FFAR1CACNA1CSCN5AMLNR | |
| SCHEMBL6856896 | 0.83 | HTR1A (0.52) | FFAR4FFAR1CACNA1CSCN5AMLNR | |
| SCHEMBL15210953 | 0.80 | HTT (0.60) | FFAR4FFAR1HTR1AADRA2AADRA2B | |
| SCHEMBL6846316 | 0.80 | HTR1A (0.49) | FFAR4FFAR1CACNA1CSCN5AMLNR | |
| SCHEMBL15210950 | 0.80 | HTT (0.60) | FFAR4FFAR1HTR1AADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102180855-A | Method for purifying Nebivolol intermediate | ZHEJIANG HUAHAI PHARM CO LTD | 2011-09-14 | — | — | CN | claimed |
| CN-102180856-A | Preparation method for 6-fluorine-3,4-dihydro-2H-1-benzopyran-2-ethyl formate | ZHEJIANG HUAHAI PHARM CO LTD | 2011-09-14 | — | — | CN | claimed |
| CN-102180855-A | Method for purifying Nebivolol intermediate | ZHEJIANG HUAHAI PHARM CO LTD | 2011-09-14 | — | — | CN | disclosed |
| CN-102180856-A | Preparation method for 6-fluorine-3,4-dihydro-2H-1-benzopyran-2-ethyl formate | ZHEJIANG HUAHAI PHARM CO LTD | 2011-09-14 | — | — | CN | disclosed |
| CN-101020681-A | Synthesis process of 6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol | UNIV ZHEJIANG (CN) | 2007-08-22 | — | — | CN | disclosed |