Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 2/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.49 |
| ▸ | MLNR | O43193 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27697367 | 0.90 | FFAR4 (0.58) | CACNA1CSCN5AMLNRADRB2ADRB1 | |
| SCHEMBL6856896 | 0.84 | HTR1A (0.52) | CACNA1CSCN5AMLNRADRB2ADRB1 | |
| SCHEMBL6856918 | 0.84 | HTR1A (0.52) | CACNA1CSCN5AMLNRADRB2ADRB1 | |
| SCHEMBL14681243 | 0.84 | HTR1A (0.52) | CACNA1CSCN5AMLNRADRB2ADRB1 | |
| SCHEMBL28857157 | 0.82 | ITGB3 (0.54) | CACNA1CSCN5AMLNRADRB2ADRB1 | |
| SCHEMBL27755780 | 0.82 | ITGB3 (0.54) | CACNA1CSCN5AMLNRADRB2ADRB1 | |
| SCHEMBL28857113 | 0.82 | ITGB3 (0.54) | CACNA1CSCN5AMLNRADRB2ADRB1 | |
| SCHEMBL6846316 | 0.81 | HTR1A (0.49) | CACNA1CSCN5AMLNRADRB2ADRB1 | |
| SCHEMBL19174388 | 0.81 | HTR1A (0.49) | CACNA1CSCN5AMLNRADRB2ADRB1 | |
| SCHEMBL12846782 | 0.81 | SLC6A2 (0.49) | CACNA1CSCN5AMLNRADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104016954-A | Method for preparing and purifying nebivolol intermediate | CHANGZHOU NO 4 PHARMACEUTICAL FACTORY CO LTD | 2014-09-03 | — | — | CN | disclosed |