Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 3/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 6/20 | 0.39 |
| ▸ | BCR | P11274 | 2/20 | 0.38 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27718391 | 0.86 | P4HA1 (0.46) | L3MBTL1HPGDSMRGPRX4ABL1CSNK2A2 | |
| SCHEMBL28740679 | 0.79 | LMNA (0.48) | HPGDSMRGPRX4LMNA | |
| SCHEMBL5128240 | 0.78 | RXFP1 (0.56) | MAPK1KDM4EL3MBTL1HPGDSMRGPRX4 | |
| SCHEMBL29651074 | 0.73 | MAPK1 (0.69) | MAPK1KDM4EL3MBTL1HPGDSSPR | |
| SCHEMBL70712 | 0.73 | MAPK1 (0.69) | MAPK1KDM4EL3MBTL1HPGDSSPR | |
| SCHEMBL29651058 | 0.73 | MAPK1 (0.69) | MAPK1KDM4EL3MBTL1HPGDSSPR | |
| SCHEMBL7317667 | 0.72 | HPGDS (0.57) | MAPK1KDM4EL3MBTL1HPGDSLMNA | |
| SCHEMBL27698017 | 0.72 | DHODH (0.43) | KDM4EL3MBTL1MRGPRX4ABL1TLR7 | |
| SCHEMBL34469486 | 0.72 | ABL1 (0.54) | MAPK1L3MBTL1MRGPRX4ABL1BCR | |
| SCHEMBL2743634 | 0.70 | BRAF (0.65) | MAPK1KDM4EL3MBTL1MRGPRX4VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101151244-B | Histamine H3 receptor agents, preparation and therapeutic uses | LILLY CO ELI | 2014-09-03 | — | — | CN | disclosed |
| CN-101151244-A | Histamine H3 receptor agents, preparation and therapeutic uses | LILLY CO ELI (US) | 2008-03-26 | — | — | CN | disclosed |