Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 6/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.51 |
| ▸ | PDE4A | P27815 | 4/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.51 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2788405 | 0.91 | PDE4A (0.51) | PDE4DPDE4BPDE4APDE4CPDE7A | |
| SCHEMBL2786982 | 0.90 | PDE4D (0.41) | PDE4DPDE4BPDE4APDE4CPDE7A | |
| SCHEMBL2785822 | 0.89 | PDE4B (0.41) | PDE4DPDE4BPDE4APDE4CPDE7A | |
| SCHEMBL2787871 | 0.89 | PDE4D (0.40) | PDE4DPDE4BPDE4APDE4CPDE7A | |
| SCHEMBL2789297 | 0.87 | PDE4A (0.47) | PDE4DPDE4BPDE4APDE4CPDE7A | |
| SCHEMBL2788977 | 0.86 | PDE4A (0.64) | PDE4DPDE4BPDE4APDE4CPDE7A | |
| SCHEMBL2770600 | 0.86 | PDE4A (0.47) | PDE4DPDE4BPDE4APDE4CPDE7A | |
| SCHEMBL2769822 | 0.81 | PDE4A (0.75) | PDE4DPDE4BPDE4APDE4CPDE7A | |
| SCHEMBL2772806 | 0.79 | KDM4E (0.48) | PDE4DPDE4BPDE4APDE4CMAPT | |
| SCHEMBL2785376 | 0.79 | PDE4A (0.54) | PDE4DPDE4BPDE4APDE4CPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076564-A2 | ISOCHROMENONES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-07-08 | — | — | WO | disclosed |