Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2788405 | 0.95 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2770600 | 0.89 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2791143 | 0.89 | DHODH (0.42) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2805301 | 0.88 | PTGES (0.41) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2769824 | 0.87 | PDE4D (0.51) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2788977 | 0.84 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2789292 | 0.82 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2772806 | 0.82 | KDM4E (0.48) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL2771444 | 0.81 | SMPD1 (0.42) | PDE4APDE4BPDE4CPDE4DPDE7A | |
| SCHEMBL2773803 | 0.81 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076564-A2 | ISOCHROMENONES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-07-08 | — | — | WO | disclosed |