Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2771578 | 0.92 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDNPC1CA1 | |
| SCHEMBL2772268 | 0.91 | KMT2A (0.44) | KDM4EALDH1A1HPGDNPC1CA1 | |
| SCHEMBL2771225 | 0.91 | PTGES (0.54) | KDM4EHPGDPOLBKMT2AMEN1 | |
| SCHEMBL2771320 | 0.91 | PTGES (0.54) | KDM4EALDH1A1HPGDNPC1CA1 | |
| SCHEMBL2772036 | 0.91 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDNPC1CA1 | |
| SCHEMBL2771247 | 0.90 | PDE4A (0.46) | KDM4EALDH1A1HPGDNPC1TP53 | |
| SCHEMBL2773020 | 0.90 | KMT2A (0.43) | KDM4EALDH1A1HPGDNPC1CA1 | |
| SCHEMBL2773724 | 0.90 | CYP1A1 (0.46) | KDM4EALDH1A1HPGDNPC1TP53 | |
| SCHEMBL2771444 | 0.90 | SMPD1 (0.42) | KDM4EALDH1A1HPGDNPC1CA1 | |
| SCHEMBL2773803 | 0.90 | PDE4A (0.41) | KDM4EALDH1A1HPGDNPC1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076564-A2 | ISOCHROMENONES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-07-08 | — | — | WO | disclosed |