Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 6/20 | 0.41 |
| ▸ | PDE4A | P27815 | 4/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2769824 | 0.89 | PDE4D (0.51) | PDE4BPDE4APDE4CPDE4DPDE7A | |
| SCHEMBL2773020 | 0.88 | KMT2A (0.43) | MEN1KMT2APSMD14MMP2BLM | |
| SCHEMBL2791143 | 0.88 | DHODH (0.42) | PDE4BPDE4APDE4CPDE4DPDE7A | |
| SCHEMBL2772268 | 0.87 | KMT2A (0.44) | PDE4BPDE4APDE4CPDE4DPDE7A | |
| SCHEMBL2786982 | 0.87 | PDE4D (0.41) | PDE4BPDE4APDE4CPDE4DPDE7A | |
| SCHEMBL2787889 | 0.86 | PDE4A (0.38) | PDE4BPDE4APDE4CPDE4DPDE7A | |
| SCHEMBL2787871 | 0.86 | PDE4D (0.40) | PDE4BPDE4APDE4CPDE4DPDE7A | |
| SCHEMBL2785816 | 0.82 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4DPDE7A | |
| SCHEMBL2788405 | 0.80 | PDE4A (0.51) | PDE4BPDE4APDE4CPDE4DPDE7A | |
| SCHEMBL2772806 | 0.78 | KDM4E (0.48) | PDE4BPDE4APDE4CPDE4DMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010076564-A2 | ISOCHROMENONES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-07-08 | — | — | WO | disclosed |