SCHEMBL27698293

SCHEMBL27698293

O=C=NNCc1ccc(Sc2ccc(CNN=C=O)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
CYP1A2 P05177 3/20 0.33
CYP2C9 P11712 3/20 0.33
CYP2C19 P33261 3/20 0.33
CYP3A4 P08684 3/20 0.33
RAB9A P51151 4/20 0.33
NPC1 O15118 3/20 0.33
MAPT P10636 2/20 0.33
PTPN1 P18031 1/20 0.32
PTPRZ1 P23471 1/20 0.32
PTGIR P43119 1/20 0.32
RECQL P46063 1/20 0.32
TSHR P16473 1/20 0.31
MITF O75030 1/20 0.31
XBP1 P17861 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
NOD2 Q9HC29 1/20 0.31
CYP2D6 P10635 1/20 0.30
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6232801 0.74 FFAR1 (0.44)
SCHEMBL331497 0.69 MIF (0.36) CYP3A4TSHRSLC6A4
SCHEMBL6233067 0.67 CHRM2 (0.50) MEN1KMT2ACYP1A2CYP2C19CYP3A4
SCHEMBL27422643 0.63 NR1H2 (0.44) MEN1KMT2ACYP1A2CYP2C9CYP2C19
SCHEMBL484003 0.61 CYP3A4 (0.54) CYP1A2CYP3A4TSHR
SCHEMBL9615170 0.61 NR1H2 (0.32) CYP3A4TSHR
SCHEMBL11761097 0.59 ALDH1A1 (0.47) CYP1A2CYP2C9CYP2C19CYP3A4RAB9A
Benzene SCHEMBL8927676 0.58 GABRA1 (0.32)
SCHEMBL5658030 0.57 MIF (0.48) MEN1KMT2ACYP3A4MAPT
SCHEMBL10383070 0.57 TSHR (0.48) MEN1KMT2ACYP1A2CYP2C9CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101006114-B Polymerisable composition containing an odour masking agent and a perfume, an optical lens and a production method ESSILOR INT 2011-09-21 CN disclosed
CN-101006114-A Polymerisable composition containing an odour masking agent and a perfume, an optical lens and a production method ESSILOR INT (FR) 2007-07-25 CN disclosed