Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | PTPRZ1 | P23471 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549836 | 0.81 | THRB (0.54) | NR1H2PTPRZ1PTPN1PTGIRTHRB | |
| SCHEMBL6540019 | 0.70 | NR1H2 (0.52) | NR1H2THRBMEN1KMT2AMAPT | |
| SCHEMBL10887327 | 0.67 | TSHR (0.48) | NR1H2NPC1RAB9AMITFXBP1 | |
| SCHEMBL15826670 | 0.67 | ESR1 (0.70) | NR1H2PTPN1IDO1NPC1RAB9A | |
| SCHEMBL6718210 | 0.67 | ARG1 (0.57) | NPSR1CYP1A2TSHRMAPK1MAPT | |
| SCHEMBL14390455 | 0.64 | NR1H2 (0.64) | NR1H2IDO1SLC6A4CYP3A4MEN1 | |
| SCHEMBL588786 | 0.64 | CA2 (0.56) | NR1H2SLC6A4CYP3A4TSHRMAPK1 | |
| SCHEMBL10914949 | 0.63 | NR1H2 (1.00) | NR1H2THRBNPC1RAB9ACYP3A4 | |
| SCHEMBL29726 | 0.63 | NR1H2 (1.00) | NR1H2THRBNPC1RAB9ACYP3A4 | |
| SCHEMBL576175 | 0.62 | TP53 (0.48) | NR1H2IDO1SLC6A4CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1045005-C | Novel bisoxadiazolidine derivative | YAMANOUCHI PHARMA CO LTD (JP) | 1999-09-08 | — | — | CN | disclosed |
| CN-1122133-A | Novel bis-oxadiazolidine derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 1996-05-08 | — | — | CN | disclosed |