Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | TKT | P29401 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | FHIT | P49789 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27784109 | 0.85 | ALDH1A1 (0.41) | ALDH1A1CYP1A2NOS1HPGDHSD17B10 | |
| SCHEMBL27698663 | 0.82 | ALDH1A1 (0.36) | ALDH1A1CYP1A2TKTHPGDHTT | |
| SCHEMBL28594511 | 0.79 | HRH2 (0.54) | ALDH1A1CYP1A2TKTFBP1 | |
| SCHEMBL25916370 | 0.76 | NOS1 (0.41) | ALDH1A1CYP1A2NOS1L3MBTL1HSD17B10 | |
| SCHEMBL28697722 | 0.75 | ALDH1A1 (0.39) | ALDH1A1CYP1A2NOS1HPGDHTT | |
| SCHEMBL6815280 | 0.74 | NOS1 (0.46) | ALDH1A1CYP1A2NOS1TKTTSHR | |
| SCHEMBL28257480 | 0.74 | ALDH1A1 (0.47) | ALDH1A1CYP1A2HPGDTSHRHSD17B10 | |
| SCHEMBL999513 | 0.73 | SMN1; SMN2 (0.53) | ALDH1A1CYP1A2HPGDHSD17B10POLB | |
| SCHEMBL750253 | 0.71 | GAA (0.54) | ALDH1A1CYP1A2NOS1HPGDHTT | |
| SCHEMBL6010112 | 0.71 | HTT (0.38) | ALDH1A1CYP1A2TKTHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101137631-A | Heteroaromatic glucokinase activators | NOVO NORDISK AS JEPPESEN LONE (US) | 2008-03-05 | — | — | CN | disclosed |