Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417449 | 0.81 | NOS1 (0.43) | NOS1HSD17B10ALDH1A1CYP1A2MAPT | |
| SCHEMBL6815280 | 0.77 | NOS1 (0.46) | NOS1HSD17B10ALDH1A1CYP1A2HRH2 | |
| SCHEMBL27698665 | 0.76 | ALDH1A1 (0.41) | NOS1HSD17B10ALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL999649 | 0.75 | HRH2 (0.59) | ALDH1A1ITGB3ITGA2BCYP1A2HRH2 | |
| SCHEMBL28257480 | 0.73 | ALDH1A1 (0.47) | HSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL25328666 | 0.72 | — | — | |
| SCHEMBL2281694 | 0.71 | LDHA (0.40) | HSD17B10ALDH1A1HDAC6L3MBTL1NPSR1 | |
| SCHEMBL28515157 | 0.70 | HDAC6 (0.50) | ALDH1A1HDAC6L3MBTL1NPSR1APEX1 | |
| SCHEMBL27784109 | 0.70 | ALDH1A1 (0.41) | NOS1HSD17B10ALDH1A1CYP1A2MAPT | |
| SCHEMBL5911688 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141262-A1 | BAX ACTIVATORS AND USE THEREOF | IPSEN PHARMA S.A.S. (FR) | 2023-07-27 | — | — | WO | disclosed |