Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 4/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5750878 | 0.92 | THRA (0.67) | THRATHRBFFAR4CTSLCTSS | |
| SCHEMBL3685248 | 0.80 | THRA (0.49) | THRATHRBLMNA | |
| SCHEMBL27679978 | 0.77 | THRA (0.45) | THRATHRBFFAR4TBXAS1 | |
| SCHEMBL4896502 | 0.73 | THRB (1.00) | THRATHRBLMNA | |
| SCHEMBL5750875 | 0.71 | THRA (0.43) | THRATHRB | |
| SCHEMBL440247 | 0.71 | XDH (0.41) | THRATHRB | |
| SCHEMBL3684301 | 0.70 | THRA (0.71) | THRATHRBFFAR4S1PR1 | |
| SCHEMBL28853251 | 0.69 | CNR1 (0.40) | THRATHRB | |
| SCHEMBL3680505 | 0.69 | CCNC (0.49) | THRATHRBFFAR4CTSLCTSS | |
| SCHEMBL5075337 | 0.68 | THRA (0.54) | THRATHRBFFAR4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101031539-A | Substituted arylalkanoic acid derivatives and use thereof | ASAHI KASEI PHAMA CORP (JP) | 2007-09-05 | — | — | CN | disclosed |