Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12672298 | 0.80 | GSK3B (0.44) | ALDH1A1HTTKMT2AMEN1MAPT | |
| SCHEMBL1231890 | 0.79 | KDM4C (0.52) | ALDH1A1HTTKMT2AL3MBTL1MEN1 | |
| SCHEMBL4444121 | 0.79 | KDM4C (0.52) | ALDH1A1HTTKMT2AL3MBTL1MEN1 | |
| SCHEMBL8597846 | 0.75 | FAAH (0.44) | ALDH1A1LMNAHTTKMT2AMEN1 | |
| SCHEMBL11718666 | 0.74 | TDP1 (0.49) | ALDH1A1LMNAHTTKMT2AL3MBTL1 | |
| SCHEMBL12672297 | 0.74 | HTT (0.45) | ALDH1A1LMNAHTTKMT2AL3MBTL1 | |
| SCHEMBL28753709 | 0.73 | HPGD (0.53) | ALDH1A1LMNAHPGDHTTMAPT | |
| SCHEMBL3329624 | 0.73 | CYP1A2 (0.57) | ALDH1A1LMNAHTTKMT2AL3MBTL1 | |
| SCHEMBL3329616 | 0.73 | CYP1A2 (0.57) | ALDH1A1LMNAHTTKMT2AL3MBTL1 | |
| SCHEMBL9850820 | 0.72 | ALDH1A1 (0.60) | ALDH1A1HPGDMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101166739-A | Substituted pyrrolopyridines, compositions containing them, process for their preparation and their use | AVENTIS PHARMA SA (FR) | 2008-04-23 | — | — | CN | disclosed |