Benzylamine

Benzylamine

SCHEMBL27699388

N=O.NCc1ccccc1

nearest known ligand 0.82

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 4/20 0.82
TAAR1 Q96RJ0 4/20 0.59
CYP1A2 P05177 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
TSHR P16473 1/20 0.56
CYP2C19 P33261 1/20 0.56
MAOB P27338 2/20 0.50
CYP2A6 P11509 1/20 0.50
HTR2A P28223 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
PNMT P11086 1/20 0.48
ENPP2 Q13822 1/20 0.48
HRH3 Q9Y5N1 1/20 0.48
HTR6 P50406 1/20 0.46
CALM1 P0DP23 1/20 0.45
MAOA P21397 2/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19242392 0.91 LOXL2 (1.00) LOXL2TAAR1CYP1A2CYP2D6CYP2C9
Benzylamine SCHEMBL1331207 0.91
Benzylamine SCHEMBL10707644 0.91 LOXL2 (1.00) LOXL2TAAR1CYP1A2CYP2D6CYP2C9
Benzylamine SCHEMBL5481672 0.91 LOXL2 (1.00) LOXL2TAAR1CYP1A2CYP2D6CYP2C9
Benzylamine SCHEMBL373 0.91
Benzylamine SCHEMBL3793057 0.88 LOXL2 (0.82) LOXL2TAAR1CYP1A2CYP2D6CYP2C9
Benzylamine SCHEMBL3793054 0.88 LOXL2 (0.82) LOXL2TAAR1CYP1A2CYP2D6CYP2C9
Benzylamine SCHEMBL23044734 0.88 LOXL2 (0.93) LOXL2TAAR1CYP1A2CYP2D6CYP2C9
Benzylamine SCHEMBL424060 0.88
Benzylamine SCHEMBL1245462 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100383112-C Method for reducing nitroxylbenzyl amine compound to amino-benzylamine hydrochloride UNIV TSINGHUA (CN) 2008-04-23 CN disclosed