Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | GRN | P28799 | 2/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15148105 | 0.81 | GRN (0.48) | MEN1HPGDKMT2ANR1H3NR1H2 | |
| SCHEMBL12632315 | 0.81 | HPGD (0.65) | MEN1HPGDKMT2ANR1H3NR1H2 | |
| SCHEMBL12572958 | 0.78 | MEN1 (0.47) | MEN1HPGDKMT2ANR1H3NR1H2 | |
| SCHEMBL4134838 | 0.77 | GRN (0.74) | MEN1HPGDKMT2AGRNSORT1 | |
| SCHEMBL4106614 | 0.77 | SMN1; SMN2 (0.50) | MEN1KMT2ANR1H3NR1H2POLB | |
| SCHEMBL1591305 | 0.76 | MPO (0.44) | MEN1HPGDKMT2APOLBTSHR | |
| SCHEMBL16423120 | 0.74 | PTGS1 (0.58) | MEN1HPGDKMT2ANR1H3NR1H2 | |
| SCHEMBL19584627 | 0.73 | NR1H2 (0.44) | MEN1HPGDKMT2ANR1H3NR1H2 | |
| SCHEMBL4130184 | 0.73 | ALDH1A1 (0.49) | MEN1HPGDKMT2APOLBTSHR | |
| SCHEMBL5367786 | 0.73 | TSHR (0.39) | MEN1HPGDKMT2AGRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101166720-A | Activator of peroxisome proliferator activated receptor delta | NIPPON CHEMIPHAR CO (JP) | 2008-04-23 | — | — | CN | disclosed |