Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 6/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9944380 | 0.81 | NPC1 (0.60) | MEN1KMT2ANPC1RAB9ACA12 | |
| SCHEMBL2204650 | 0.81 | MAOB (0.65) | HPGDSMAOBMEN1KMT2ANPC1 | |
| SCHEMBL29373133 | 0.77 | MGAM (0.62) | HPGDSMAOBMEN1KMT2APDGFRB | |
| SCHEMBL7955678 | 0.77 | MGAM (0.62) | HPGDSMAOBMEN1KMT2APDGFRB | |
| SCHEMBL8337219 | 0.76 | ALDH1A1 (0.48) | MEN1KMT2ANPC1RAB9ACA12 | |
| SCHEMBL29813276 | 0.76 | HPGDS (0.61) | HPGDSMAOBPDGFRBPDGFRASMN1; SMN2 | |
| SCHEMBL17785433 | 0.76 | MAOB (0.52) | HPGDSMAOBPDGFRBPDGFRAALDH1A1 | |
| SCHEMBL20799489 | 0.74 | ALDH1A1 (0.53) | MEN1KMT2ANPC1RAB9APDGFRB | |
| SCHEMBL29940590 | 0.72 | RXFP1 (0.53) | HPGDSALOX15MAPTNPSR1 | |
| SCHEMBL24358178 | 0.72 | HPGDS (0.48) | HPGDSMAOBPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163700-A | Triamine derivative | DAIICHI SEIYAKU CO (JP) | 2008-04-16 | — | — | CN | disclosed |