Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20799494 | 0.87 | L3MBTL1 (0.47) | ALDH1A1HPGDLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL20799483 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HPGDLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL17384693 | 0.81 | LMNA (0.52) | ALDH1A1HPGDLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL5553780 | 0.78 | MGAM (0.51) | ALDH1A1HPGDLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL20799492 | 0.77 | MAOB (0.47) | ALDH1A1HPGDLMNASMN1; SMN2L3MBTL1 | |
| Hydrogen Sulfide SCHEMBL28775857 | 0.77 | MGAM (0.50) | ALDH1A1HPGDLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL19020788 | 0.76 | KDM4E (0.49) | ALDH1A1HPGDLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL9944380 | 0.74 | NPC1 (0.60) | ALDH1A1HPGDLMNAL3MBTL1KMT2A | |
| Urea SCHEMBL6016094 | 0.74 | MGAM (0.47) | ALDH1A1HPGDLMNASMN1; SMN2KMT2A | |
| SCHEMBL27699424 | 0.74 | HPGDS (0.46) | ALDH1A1HPGDLMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10227355-B2 | Quinoline derivatives and preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2019-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10227355-B2 | Quinoline derivatives and preparation thereof | ABL1, FLT3, MAP3K7 | ALDH1A1 2096/4885HPGD 1589/4885LMNA 2995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.