Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1476708 | 0.79 | FFAR1 (0.49) | CHRNA7HRH3CYP3A4NAMPT | |
| SCHEMBL18529756 | 0.78 | HRH3 (0.44) | CHRNA7HRH3KDM1ACYP3A4NAMPT | |
| SCHEMBL1473448 | 0.72 | HRH3 (0.40) | CHRNA7HRH3CYP3A4NAMPT | |
| SCHEMBL15604151 | 0.70 | KDM4E (0.39) | CHRNA7 | |
| SCHEMBL13141209 | 0.68 | ESR2 (0.46) | CHRNA7 | |
| Formic Acid SCHEMBL27699507 | 0.68 | TRPM8 (0.32) | TRPV1 | |
| SCHEMBL20249129 | 0.68 | KMT2A (0.36) | CHRNA7 | |
| SCHEMBL12165287 | 0.68 | CHRNB2 (0.56) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL22388847 | 0.67 | SMN1; SMN2 (0.47) | CHRNA7 | |
| SCHEMBL20249182 | 0.67 | ESR2 (0.46) | CHRNA7HRH3CYP3A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101160285-A | Substituted sulfonylaminoarylmethyl cyclopropanecarboxamide as vr1 receptor antagonists | PFIZER (US) | 2008-04-09 | — | — | CN | disclosed |