Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 1.00 |
| ▸ | FAAH | O00519 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28601911 | 0.92 | HIF1A (0.85) | HIF1AFAAHNPC1RAB9AEGLN1 | |
| SCHEMBL28607757 | 0.92 | HIF1A (1.00) | HIF1AFAAHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28608835 | 0.92 | HIF1A (0.85) | HIF1AFAAHNPC1RAB9AEGLN1 | |
| SCHEMBL28601903 | 0.91 | HIF1A (0.83) | HIF1AFAAHNPC1RAB9A | |
| SCHEMBL28596560 | 0.91 | HIF1A (0.83) | HIF1AFAAHNPC1RAB9AEGLN1 | |
| SCHEMBL28347634 | 0.91 | HIF1A (1.00) | HIF1AFAAHNPC1RAB9AEGLN1 | |
| SCHEMBL28601907 | 0.90 | HIF1A (0.81) | HIF1AFAAHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28601917 | 0.89 | HIF1A (1.00) | HIF1AFAAHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28614480 | 0.89 | HIF1A (0.79) | HIF1AFAAHMAPT | |
| SCHEMBL28344792 | 0.87 | HIF1A (0.76) | HIF1AFAAHNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112716950-B | New application of N- (2-phenylethyl) -5-phenyl-pyridine-2-formamide and medicine thereof | 安徽医科大学 | 2022-04-01 | — | — | CN | claimed |
| CN-112716950-A | New application of N- (2-phenylethyl) -5-phenyl-pyridine-2-formamide and medicine thereof | 安徽医科大学 | 2021-04-30 | — | — | CN | claimed |
| CN-112716950-B | New application of N- (2-phenylethyl) -5-phenyl-pyridine-2-formamide and medicine thereof | 安徽医科大学 | 2022-04-01 | — | — | CN | disclosed |
| CN-112716950-B | New application of N- (2-phenylethyl) -5-phenyl-pyridine-2-formamide and medicine thereof | 安徽医科大学 | 2022-04-01 | — | — | CN | disclosed |
| CN-112716950-B | New application of N- (2-phenylethyl) -5-phenyl-pyridine-2-formamide and medicine thereof | 安徽医科大学 | 2022-04-01 | — | — | CN | disclosed |
| CN-110407824-B | Aryl formamide compound and preparation method, pharmaceutical composition and application thereof | 安徽医科大学 | 2021-07-02 | — | — | CN | disclosed |
| CN-112716950-A | New application of N- (2-phenylethyl) -5-phenyl-pyridine-2-formamide and medicine thereof | 安徽医科大学 | 2021-04-30 | — | — | CN | disclosed |
| CN-112716950-A | New application of N- (2-phenylethyl) -5-phenyl-pyridine-2-formamide and medicine thereof | 安徽医科大学 | 2021-04-30 | — | — | CN | disclosed |
| CN-112716950-A | New application of N- (2-phenylethyl) -5-phenyl-pyridine-2-formamide and medicine thereof | 安徽医科大学 | 2021-04-30 | — | — | CN | disclosed |
| CN-110407824-A | Aryl methanamide compounds and preparation method thereof, pharmaceutical composition and purposes | UNIV ANHUI MEDICAL | 2019-11-05 | — | — | CN | disclosed |