Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5743776 | 0.86 | PPARG (0.54) | SLC6A4PPARGPPARASLC6A2SLC6A3 | |
| SCHEMBL4283538 | 0.84 | SLC6A2 (0.47) | SLC6A4PPARGPPARASLC6A2SLC6A3 | |
| SCHEMBL27986499 | 0.81 | MME (0.45) | PPARGPPARAMEN1KMT2AACACB | |
| SCHEMBL27963924 | 0.81 | SLC7A5 (0.52) | SLC6A2 | |
| SCHEMBL11165041 | 0.80 | SLC6A2 (0.43) | SLC6A4PPARGPPARASLC6A2SLC6A3 | |
| SCHEMBL15451590 | 0.80 | NOS2 (0.46) | PPARGPPARASLC6A2SLC6A3KMT2A | |
| SCHEMBL17763412 | 0.78 | CYP1A2 (0.56) | — | |
| SCHEMBL15446358 | 0.76 | PPARG (0.46) | PPARGPPARAACACB | |
| SCHEMBL27975288 | 0.75 | CYP3A4 (0.46) | SLC6A4SLC6A2SLC6A3CYP2C9CYP2C19 | |
| SCHEMBL9481327 | 0.75 | SLC6A4 (0.58) | SLC6A4PPARGPPARASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104011043-A | Quinuclidine esters of 1-azaheterocyclylacetic acid as antimuscarinic agents, process for their preparation and medicinal compositions thereof | CHIESI FARMA SPA | 2014-08-27 | — | — | CN | disclosed |
| CN-86102389-A | The preparation and the application thereof of the aralkyl compound that the azoles base replaces | — | 1987-01-21 | — | — | CN | disclosed |