Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 6/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28168182 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4ETDP1POLB | |
| SCHEMBL27450285 | 0.79 | TDP1 (0.48) | ALDH1A1ALOX15KDM4ETDP1MAPT | |
| SCHEMBL28168179 | 0.79 | APP (0.39) | ALDH1A1HPGDALOX15KDM4EHSD17B10 | |
| SCHEMBL27294646 | 0.78 | HTT (0.43) | ALDH1A1ALOX15KDM4EPOLBCHRNB2 | |
| SCHEMBL27297501 | 0.76 | CYP2A6 (0.55) | ALDH1A1HPGDKDM4EHSD17B10LMNA | |
| SCHEMBL27350154 | 0.75 | — | — | |
| SCHEMBL27809709 | 0.75 | ALDH1A1 (0.41) | ALDH1A1TDP1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL27889712 | 0.73 | ALDH1A1 (0.47) | ALDH1A1HPGDALOX15KDM4EHSD17B10 | |
| SCHEMBL27787739 | 0.71 | MAPT (0.42) | ALDH1A1HPGDKDM4ETDP1CA12 | |
| SCHEMBL14167899 | 0.70 | ALDH1A1 (0.43) | ALDH1A1HPGDALOX15KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107056799-B | The double heptene sulfamide compounds of suberic acid monoanilide group oxygen bridge, its synthetic method, application and anti-breast cancer medicines composition | 武汉宏兹生物技术有限公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-101495463-B | Seven-membered ring compound, production method thereof and pharmaceutical use thereof | DAIICHI SANKYO CO LTD | 2012-08-15 | — | — | CN | disclosed |
| CN-102127023-A | 7-membered ring compound, process for producing the same, and use thereof | DAIICHI ASUBIO PHARMA CO LTD | 2011-07-20 | — | — | CN | disclosed |
| CN-101160290-B | 7-membered ring compound, process for producing the same, and pharmaceutical use thereof | DAIICHI SANKYO CO LTD | 2011-01-19 | — | — | CN | disclosed |
| CN-101495463-A | Seven-membered ring compound, production method thereof and pharmaceutical use thereof | ASUBIO PHARMA CO LTD (JP) | 2009-07-29 | — | — | CN | disclosed |
| CN-101160290-A | 7-membered ring compound, process for producing the same, and pharmaceutical use thereof | ASUBIO PHARMA CO LTD (JP) | 2008-04-09 | — | — | CN | disclosed |