Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27590241 | 0.81 | MAPT (0.51) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28168182 | 0.76 | ALDH1A1 (0.46) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL1561000 | 0.76 | NR4A1 (0.62) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28168179 | 0.74 | APP (0.39) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27294646 | 0.74 | HTT (0.43) | ALDH1A1MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL3774058 | 0.72 | ALDH1A1 (0.72) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27700429 | 0.71 | ALDH1A1 (0.41) | MAPTALDH1A1KDM4ETDP1RAB9A | |
| SCHEMBL27450285 | 0.71 | TDP1 (0.48) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL10778839 | 0.71 | SMN1; SMN2 (0.52) | MAPTKMT2ATDP1GFERRAB9A | |
| SCHEMBL20527388 | 0.70 | RAB9A (0.43) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801935-B | Uracil or thymine derivatives for the treatment of hepatitis C | ABBOTT LAB | 2014-12-03 | — | — | CN | disclosed |
| CN-101801935-A | Uracil or thymine derivatives for the treatment of hepatitis C | ABBOTT LAB | 2010-08-11 | — | — | CN | disclosed |