SCHEMBL27701035

SCHEMBL27701035

NNC(N)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.52
F2 P00734 1/20 0.52
AOC3 Q16853 5/20 0.48
CTSD P07339 1/20 0.43
HTR2A P28223 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
ADRA2A P08913 1/20 0.41
ADRA2C P18825 1/20 0.41
LMNA P02545 1/20 0.41
HIF1A Q16665 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17266149 0.80 MAOA (0.43) DPP4F2AOC3
SCHEMBL16900469 0.80 DPP4 (0.55) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL7187017 0.80 DPP4 (0.55) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL26414224 0.78 DPP4 (0.52) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL10233680 0.76 DPP4 (0.50) DPP4F2AOC3CTSDADRA2A
SCHEMBL16935659 0.76 DPP4 (0.50) DPP4F2HTR2ATAAR1ADRA2A
SCHEMBL16774204 0.76 DPP4 (0.50) DPP4F2AOC3HTR2ATAAR1
SCHEMBL4414443 0.74 MTOR (0.52) DPP4F2AOC3CTSDHTR2A
SCHEMBL564576 0.74 TDP1 (0.48) DPP4F2CTSDLMNA
Hydrochloric Acid SCHEMBL10786964 0.72 CYP3A4 (0.54) DPP4F2AOC3CTSDHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113773315-A Highly selective deuterated inhibitors of cyclin dependent kinase 2(CDK2) 无锡佰翱得生物科学有限公司 2021-12-10 CN disclosed
CN-112424194-A Immunomodulator, composition and preparation method thereof 贝达药业股份有限公司 2021-02-26 CN disclosed
CN-100493716-C Extraction of nickel(0) complexes from nitrile mixtures with reduced powder formation BASF AG (DE) 2009-06-03 CN disclosed
CN-101043946-A Extraction of nickel(0) complexes from nitrile mixtures with reduced powder formation BASF AG (DE) 2007-09-26 CN disclosed