Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7187017 | 0.80 | DPP4 (0.55) | DPP4F2TSHRHTR2ATAAR1 | |
| SCHEMBL16900469 | 0.80 | DPP4 (0.55) | DPP4F2TSHRHTR2ATAAR1 | |
| SCHEMBL16774204 | 0.76 | DPP4 (0.50) | DPP4F2TSHRHTR2ATAAR1 | |
| SCHEMBL16935659 | 0.76 | DPP4 (0.50) | DPP4F2TSHRHTR2ATAAR1 | |
| SCHEMBL10233680 | 0.76 | DPP4 (0.50) | DPP4F2KDM4EADRA2AADRA2C | |
| SCHEMBL8118554 | 0.75 | SIGMAR1 (0.45) | DPP4F2TSHRHTR2ATAAR1 | |
| SCHEMBL564576 | 0.74 | TDP1 (0.48) | DPP4F2TSHRKDM4EL3MBTL1 | |
| SCHEMBL22990182 | 0.72 | ADRA2A (0.46) | DPP4F2TAAR1KDM4EL3MBTL1 | |
| SCHEMBL12648940 | 0.71 | MTOR (0.55) | DPP4F2TSHRHTR2ATAAR1 | |
| SCHEMBL1436776 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018148-A1 | TETRAHYDROPYRIDOPYRIMIDINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-01-18 | — | — | US | disclosed |
| US-20230255104-A1 | Compound And Organic Light-Emitting Device Comprising Same | LG CHEM, LTD. (KR) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230255104-A1 | Compound And Organic Light-Emitting Device Comprising Same | ARL1, AR, ALG3 | DPP4 4795/4885F2 3122/4885TSHR 3621/4885 |
| US-20240018148-A1 | TETRAHYDROPYRIDOPYRIMIDINES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD | YAP1, TEAD2, TEAD1 | DPP4 3270/4885F2 2649/4885TSHR 2970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.