Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CTSV | O60911 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16169793 | 0.85 | IMPDH2 (0.69) | IMPDH2PTGS2MEN1MAPTKMT2A | |
| SCHEMBL17383846 | 0.85 | IMPDH2 (0.73) | IMPDH2PTGS2MEN1MAPTKMT2A | |
| SCHEMBL4607984 | 0.82 | ESR1 (0.69) | IMPDH2PTGS2MEN1MAPTKMT2A | |
| SCHEMBL8722197 | 0.82 | IMPDH2 (0.65) | IMPDH2PTGS2MEN1MAPTKMT2A | |
| SCHEMBL6986423 | 0.82 | IMPDH2 (0.65) | IMPDH2PTGS2MEN1MAPTKMT2A | |
| SCHEMBL7042862 | 0.81 | MAPK14 (0.81) | PTGS2MAPK14MAPTKDM4ECTSV | |
| SCHEMBL704586 | 0.81 | IMPDH2 (0.55) | IMPDH2MEN1MAPTKMT2ANPSR1 | |
| SCHEMBL19217028 | 0.81 | GSK3B (0.51) | IMPDH2PTGS2MAPK14MEN1MAPT | |
| SCHEMBL15797297 | 0.80 | GSK3B (0.64) | IMPDH2PTGS2MAPK14MEN1MAPT | |
| SCHEMBL12561582 | 0.80 | MAPT (0.55) | PTGS2MAPK14MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101087784-A | Indole acetic acids exhibiting CRTH2 receptor antagonism and uses thereof | ATHERSYS INC (US) | 2007-12-12 | — | — | CN | disclosed |