Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.48 |
| ▸ | TUBB | P07437 | 2/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28906448 | 0.82 | DRD2 (0.45) | IMPDH2LMNAHPGDTDO2TUBB4A | |
| SCHEMBL27701196 | 0.81 | IMPDH2 (0.65) | IMPDH2LMNAHPGDCYP1A2CYP2C9 | |
| SCHEMBL694132 | 0.81 | TNKS2 (0.41) | IMPDH2LMNAHPGDTUBB4ATUBB | |
| SCHEMBL17383846 | 0.81 | IMPDH2 (0.73) | IMPDH2LMNAHPGDHTR2AHTR2C | |
| SCHEMBL27681973 | 0.79 | PTGS2 (0.59) | IMPDH2LMNAHPGDTUBB4ATUBB | |
| SCHEMBL857878 | 0.76 | PIM1 (0.55) | TDO2MAPT | |
| SCHEMBL19608343 | 0.75 | ASH1L (0.57) | IMPDH2CYP1A2CYP2C9MAPTGAA | |
| SCHEMBL22899549 | 0.75 | PADI4 (0.61) | LMNAHPGDTUBB4ATUBBTUBA3C | |
| SCHEMBL12125684 | 0.74 | TAAR1 (0.48) | LMNAHPGDTDO2CYP1A2ESR2 | |
| SCHEMBL16169793 | 0.74 | IMPDH2 (0.69) | IMPDH2LMNAHPGDHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421825-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | Janssen Pharmaceutica N.V. (BE) | 2012-02-29 | — | — | EP | claimed |
| WO-2010124108-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-28 | — | — | WO | claimed |