Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL5156531 | 0.71 | OPRL1 (0.67) | OPRM1OPRL1 | |
| Bicarbonate SCHEMBL5162054 | 0.69 | OPRL1 (0.64) | OPRM1OPRL1 | |
| SCHEMBL2782210 | 0.66 | OPRL1 (0.78) | OPRM1OPRL1 | |
| SCHEMBL43810 | 0.65 | AKR1C1 (0.68) | OPRL1AKR1C1HDAC4HTTSMN1; SMN2 | |
| SCHEMBL13955288 | 0.65 | OPRM1 (0.59) | OPRM1OPRL1 | |
| SCHEMBL9818613 | 0.65 | OPRM1 (0.40) | OPRM1OPRL1HDAC4 | |
| SCHEMBL27525174 | 0.65 | AKR1C1 (0.43) | OPRM1OPRL1AKR1C1HDAC4MEN1 | |
| SCHEMBL17761202 | 0.65 | DPP4 (0.56) | AKR1C1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11500280 | 0.65 | MEN1 (0.43) | OPRM1OPRL1AKR1C1HDAC4MEN1 | |
| SCHEMBL11665387 | 0.65 | AKR1C1 (0.43) | OPRM1OPRL1AKR1C1HDAC4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101087775-A | Azole derivatives with antimuscarinic activity | CHIESI FARMA SPA (IT) | 2007-12-12 | — | — | CN | disclosed |