Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 11/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963041 | 0.66 | OPRM1 (0.44) | OPRM1OPRK1 | |
| SCHEMBL27701529 | 0.65 | OPRM1 (0.40) | OPRM1OPRL1HDAC4 | |
| SCHEMBL22101935 | 0.65 | OPRL1 (0.82) | OPRM1OPRL1OPRK1 | |
| Bicarbonate SCHEMBL5156531 | 0.65 | OPRL1 (0.67) | OPRM1OPRL1OPRK1 | |
| SCHEMBL11543475 | 0.65 | GABRA1 (0.43) | ALDH1A1 | |
| Bicarbonate SCHEMBL5162054 | 0.63 | OPRL1 (0.64) | OPRM1OPRL1OPRK1 | |
| SCHEMBL15776154 | 0.63 | AKR1C1 (0.53) | PRCPSIGMAR1ALDH1A1POLBSLC6A4 | |
| SCHEMBL11142530 | 0.62 | TP53 (0.35) | OPRM1ALDH1A1HDAC4 | |
| SCHEMBL6696399 | 0.62 | GABRA1 (0.41) | ALDH1A1 | |
| SCHEMBL7382859 | 0.61 | OPRL1 (0.50) | OPRM1OPRL1OPRK1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5015644-A | Antihyperlipidemic and antiatherosclerotic urea and carbamate compounds | WARNER-LAMBERT COMPANY (US) | 1991-05-14 | — | — | US | disclosed |