Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL28073916 | 0.91 | HTR6 (0.56) | HTR6MEN1KMT2AHTTALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL28823657 | 0.86 | HTR6 (0.55) | HTR6MEN1KMT2AHTTALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL28280131 | 0.85 | HTR6 (0.45) | HTR6MEN1KMT2AHTTALDH1A1 | |
| SCHEMBL429849 | 0.83 | HTR6 (1.00) | HTR6MEN1KMT2AHTTALDH1A1 | |
| SCHEMBL29558135 | 0.83 | HTR6 (1.00) | HTR6MEN1KMT2AHTTALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL28081145 | 0.82 | HTR6 (0.54) | HTR6HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL28794299 | 0.81 | HTR6 (0.96) | HTR6MEN1KMT2AHTTALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL27580233 | 0.81 | MEN1 (0.58) | HTR6MEN1KMT2AHTTALDH1A1 | |
| Ethoxycarbonyl Group SCHEMBL27807521 | 0.76 | CDK4 (0.38) | HTR6KMT2AHTTLMNA | |
| Ethoxycarbonyl Group SCHEMBL27487577 | 0.76 | CYP2A6 (0.42) | KMT2AHTTALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102304150-A | Phospho-indoles as HIV inhibitors | IDENIX PHARMACEUTICALS INC (US) | 2012-01-04 | — | — | CN | disclosed |
| CN-101084231-B | Phospho-indoles as HIV inhibitors | IDENIX PHARMACEUTICALS INC (US) | 2011-08-24 | — | — | CN | disclosed |
| CN-101084231-A | Phospho-indoles as HIV inhibitors | IDENIX PHARMACEUTICALS INC (US) | 2007-12-05 | — | — | CN | disclosed |