SCHEMBL429849

SCHEMBL429849

O=S(=O)(c1ccccc1)n1ccc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 12/20 1.00
HTT P42858 3/20 1.00
MEN1 O00255 3/20 1.00
KMT2A Q03164 3/20 1.00
ALDH1A1 P00352 1/20 1.00
LMNA P02545 1/20 1.00
HPGD P15428 1/20 1.00
TSHR P16473 1/20 1.00
L3MBTL1 Q9Y468 2/20 0.75
PKM P14618 1/20 0.75
MAPT P10636 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
RAPGEF4 Q8WZA2 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
POLB P06746 1/20 0.60
MET P08581 1/20 0.58
CYP2C19 P33261 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29558135 1.00 HTR6 (1.00) HTR6HTTMEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL28794299 0.98 HTR6 (0.96) HTR6HTTMEN1KMT2AALDH1A1
SCHEMBL31663420 0.90 HTR6 (0.81) HTR6HTTMEN1KMT2AALDH1A1
SCHEMBL9587047 0.86 HTR6 (0.75) HTR6HTTMEN1KMT2AALDH1A1
SCHEMBL3967709 0.86 HTR6 (0.75) HTR6HTTMEN1KMT2AALDH1A1
SCHEMBL29414854 0.86 HTR6 (0.75) HTR6HTTMEN1KMT2AALDH1A1
SCHEMBL1673252 0.86 HTR6 (0.75) HTR6HTTMEN1KMT2AALDH1A1
SCHEMBL4862697 0.86 HTT (1.00) HTR6HTTMEN1KMT2AALDH1A1
SCHEMBL1203289 0.84 HTR6 (0.73) HTR6HTTMEN1KMT2AALDH1A1
SCHEMBL30625044 0.84 HTR6 (0.72) HTR6HTTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 455 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11384076-B2 Synthesis, pharmacology and use of new and selective FMS-like tyrosine kinase 3 (FLT3) FLT3 inhibitors UNIVERSITÄT REGENSBURG (DE) 2022-07-12 US claimed
CN-101258144-B As a functional 5-HT6Aminoarylsulfonamide derivatives of ligands SUVEN LIFE SCIENCES LTD 2012-05-30 CN claimed
CN-101258144-A Aminoaryl sulphonamide derivatives as functional 5-ht6 ligands SUVEN LIFE SCIENCES LTD (IN) 2008-09-03 CN claimed
US-20060222997-A1 Adhesion improver for photosensitive resin composition and photosensitive resin composition containing same KOBAYASHI SATOSHI 2006-10-05 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
US-6106599-A Inks XEROX CORPORATION (US) 2000-08-22 US claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
CN-1033276-A Biphenyl derivatives and method for making thereof TANABE SEIYAKU CO (JP) 1989-06-07 CN claimed
EP-0316939-A2 Biphenyl derivatives, preparation method, pharmaceutical compositions comprising them and use Tanabe Seiyaku Co., Ltd. (JP) 1989-05-24 EP claimed
JP-4273857-A None JP disclosed
US-12630511-B2 Benzamide derivative, preparation method therefor, and pharmaceutical composition comprising same as active ingredient for prevention or treatment of cancer KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-05-19 US disclosed
CN-116891461-B Synthesis method of SERD intermediate 罗欣药业(上海)有限公司 2026-05-15 CN disclosed
EP-0070698-B1 HERBICIDAL INDOLE SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-11-13 EP disclosed
EP-0135781-A1 3-(Piperidinyl)- and 3-(pyrrolidinyl)-1H-indazoles, a process for their preparation and their use as a medicament HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1985-04-03 EP disclosed
US-4404277-A CYANINE DYES, SILVER HALIDE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-09-13 US disclosed
EP-0070698-A1 Herbicidal indole sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-01-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11384076-B2 Synthesis, pharmacology and use of new and selective FMS-like tyrosine kinase 3 (FLT3) FLT3 inhibitors FLT3, CSF3R, ABL1 HTR6 3062/4885HTT 4235/4885MEN1 1639/4885
US-12630511-B2 Benzamide derivative, preparation method therefor, and pharmaceutical composition comprising same as active ingredient for prevention or treatment of cancer EGFR, ERBB2, KRAS HTR6 1150/4885HTT 4213/4885MEN1 2435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.