Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27701833 | 0.82 | HDAC1 (0.35) | ALDH1A1TSHRGRIN1GRIN2AKDM4E | |
| SCHEMBL27701766 | 0.82 | GRIN1 (0.34) | ALDH1A1TSHRGRIN1GRIN2AKDM4E | |
| SCHEMBL27701908 | 0.81 | GRIN1 (0.33) | ALDH1A1GRIN1GRIN2AGAA | |
| SCHEMBL27701657 | 0.80 | HDAC1 (0.36) | GRIN1GRIN2A | |
| SCHEMBL27701642 | 0.79 | CHRNA7 (0.32) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL27701827 | 0.78 | HDAC1 (0.41) | — | |
| SCHEMBL27722379 | 0.78 | GRIN1 (0.32) | GRIN1GRIN2A | |
| SCHEMBL27701635 | 0.78 | HDAC1 (0.33) | GRIN1GRIN2A | |
| SCHEMBL27701632 | 0.74 | HDAC1 (0.35) | — | |
| SCHEMBL27701686 | 0.71 | HDAC1 (0.35) | ALDH1A1TSHRGRIN1GRIN2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163703-B | Imidazo [1,2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG | 2010-12-15 | — | — | CN | disclosed |
| CN-101163703-A | Imidazo [1, 2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG (CH) | 2008-04-16 | — | — | CN | disclosed |