SCHEMBL27701657

SCHEMBL27701657

CCc1cccc2nc(C(C)(C)C)c(NCC(=O)NO)n12

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 19/20 0.36
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27701639 0.86 HDAC1 (0.35) HDAC1
SCHEMBL27722205 0.86 ALDH1A1 (0.36) HDAC1
SCHEMBL27722221 0.85 HDAC1 (0.35) HDAC1
SCHEMBL27701786 0.85 MEN1 (0.38) HDAC1
SCHEMBL27701833 0.84 HDAC1 (0.35) HDAC1GRIN1GRIN2A
SCHEMBL27701766 0.84 GRIN1 (0.34) HDAC1GRIN1GRIN2A
SCHEMBL27701908 0.82 GRIN1 (0.33) HDAC1GRIN1GRIN2A
SCHEMBL27701827 0.80 HDAC1 (0.41) HDAC1
SCHEMBL27701635 0.80 HDAC1 (0.33) HDAC1GRIN1GRIN2A
SCHEMBL27701656 0.80 MCHR1 (0.32) GRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101163703-B Imidazo [1,2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors NOVARTIS AG 2010-12-15 CN disclosed
CN-101163703-A Imidazo [1, 2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors NOVARTIS AG (CH) 2008-04-16 CN disclosed