Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27701833 | 0.93 | HDAC1 (0.35) | GRIN1GRIN2AHDAC1PDE5AGAA | |
| SCHEMBL27701827 | 0.87 | HDAC1 (0.41) | HDAC1 | |
| SCHEMBL27701635 | 0.87 | HDAC1 (0.33) | GRIN1GRIN2AHDAC1 | |
| SCHEMBL27701766 | 0.85 | GRIN1 (0.34) | GRIN1GRIN2AHDAC1PDE5AGAA | |
| SCHEMBL27722222 | 0.85 | ALDH1A1 (0.39) | GAARAB9AALDH1A1HTT | |
| SCHEMBL27701899 | 0.84 | GPR139 (0.33) | NPC1GAARAB9AGFERMEP1B | |
| SCHEMBL27701632 | 0.83 | HDAC1 (0.35) | HDAC1PDE5A | |
| SCHEMBL27701782 | 0.83 | NRP1 (0.32) | MEP1B | |
| SCHEMBL27701657 | 0.82 | HDAC1 (0.36) | GRIN1GRIN2AHDAC1 | |
| SCHEMBL27701686 | 0.81 | HDAC1 (0.35) | GRIN1GRIN2AHDAC1NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163703-B | Imidazo [1,2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG | 2010-12-15 | — | — | CN | disclosed |
| CN-101163703-A | Imidazo [1, 2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG (CH) | 2008-04-16 | — | — | CN | disclosed |