Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK2 | P25098 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | CTH | P32929 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isonicotinonitrile SCHEMBL27701747 | 0.87 | GRK2 (0.48) | GRK2KMT2AMEN1GAAKDM4E | |
| SCHEMBL982231 | 0.84 | — | — | |
| SCHEMBL352177 | 0.84 | — | — | |
| SCHEMBL591208 | 0.84 | — | — | |
| SCHEMBL3821801 | 0.82 | KMT2A (0.58) | KMT2AMEN1GAAKDM4EALDH1A1 | |
| SCHEMBL2449990 | 0.82 | KMT2A (0.58) | KMT2AMEN1GAAKDM4EALDH1A1 | |
| SCHEMBL1230125 | 0.82 | KMT2A (0.58) | KMT2AMEN1GAAKDM4EALDH1A1 | |
| Bromide SCHEMBL28108732 | 0.82 | ACHE (0.45) | KMT2AMEN1GAAKDM4EALDH1A1 | |
| Bromide SCHEMBL7180391 | 0.82 | ACHE (0.45) | KMT2AMEN1GAAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6901823 | 0.82 | ACHE (0.45) | KMT2AMEN1GAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101048380-B | Process for production of 2-hydroxy-4-substituted pyridines | YUKI GOSEI YAKUHIN KOGYO KK | 2012-06-20 | — | — | CN | disclosed |
| CN-101048380-A | Process for production of 2-hydroxy-4-substituted pyridines | YUKI GOSEI YAKUHIN KOGYO KK (JP) | 2007-10-03 | — | — | CN | disclosed |