Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK2 | P25098 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GRK5 | P34947 | 1/20 | 0.39 |
| ▸ | GRK3 | P35626 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isonicotinonitrile SCHEMBL27701693 | 0.87 | GRK2 (0.48) | GRK2ACHEKDM4EKMT2AMEN1 | |
| SCHEMBL740549 | 0.73 | KMT2A (0.67) | ACHEPARP15PARP10PARP2KDM4E | |
| SCHEMBL8224874 | 0.73 | KMT2A (0.67) | ACHEPARP15PARP10PARP2KDM4E | |
| Water SCHEMBL31094001 | 0.73 | CYP17A1 (0.57) | PARP15PARP10KDM4EKMT2AMEN1 | |
| SCHEMBL982231 | 0.73 | — | — | |
| SCHEMBL352177 | 0.73 | — | — | |
| SCHEMBL591208 | 0.73 | — | — | |
| SCHEMBL2449990 | 0.71 | KMT2A (0.58) | ACHEKDM4EKMT2AMEN1NPC1 | |
| SCHEMBL3821801 | 0.71 | KMT2A (0.58) | ACHEKDM4EKMT2AMEN1NPC1 | |
| SCHEMBL1230125 | 0.71 | KMT2A (0.58) | ACHEKDM4EKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101048380-A | Process for production of 2-hydroxy-4-substituted pyridines | YUKI GOSEI YAKUHIN KOGYO KK (JP) | 2007-10-03 | — | — | CN | disclosed |