⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL591208 | 1.00 | — | — | |
| SCHEMBL352177 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL6901823 | 0.97 | ACHE (0.45) | — | |
| Bromide SCHEMBL28108732 | 0.97 | ACHE (0.45) | — | |
| Bromide SCHEMBL7180391 | 0.97 | ACHE (0.45) | — | |
| Iodomethane SCHEMBL8058645 | 0.93 | ACHE (0.47) | — | |
| SCHEMBL29720380 | 0.85 | KMT2A (0.44) | — | |
| SCHEMBL9712709 | 0.85 | KMT2A (0.44) | — | |
| Isonicotinonitrile SCHEMBL27701693 | 0.84 | GRK2 (0.48) | — | |
| SCHEMBL4275683 | 0.80 | KMT2A (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112830913-A | Method for preparing 2, 5-furan diformylaldoxime | 中国科学院宁波材料技术与工程研究所 | 2021-05-25 | — | — | CN | claimed |
| CN-118206565-A | Catalytic marking reagent with phosphatidylserine targeting function and micro-region proteome marking and identifying method | 中国科学院大连化学物理研究所 | 2024-06-18 | — | — | CN | disclosed |
| CN-110606827-B | One-step method for synthesizing methylaminopyridine compounds | 西安凯立新材料股份有限公司 | 2023-03-14 | — | — | CN | disclosed |
| EP-4074709-A1 | MONOCYCLIC BETA-LACTAM COMPOUND AND USE THEREOF | Evopoint Biosciences Co., Ltd. (CN) | 2022-10-19 | — | — | EP | disclosed |
| CN-109438471-B | Tricyclic isoxazole compound and preparation method and application thereof | 中国人民解放军第二军医大学 | 2021-09-17 | — | — | CN | disclosed |
| US-11066365-B2 | 1-cyano-pyrrolidine compounds as USP30 inhibitors | MISSION THERAPEUTICS LIMITED (GB) | 2021-07-20 | — | — | US | disclosed |
| CN-113087722-A | Tricyclic isoxazole compound and preparation method and application thereof | 中国人民解放军海军军医大学 | 2021-07-09 | — | — | CN | disclosed |
| WO-2021115444-A1 | MONOCYCLIC β-LACTAM COMPOUND AND USE THEREOF | 苏州信诺维医药科技股份有限公司 | 2021-06-17 | — | — | WO | disclosed |
| CN-112830913-A | Method for preparing 2, 5-furan diformylaldoxime | 中国科学院宁波材料技术与工程研究所 | 2021-05-25 | — | — | CN | disclosed |
| US-10689345-B2 | 1-cyano-pyrrolidine compounds as USP30 inhibitors | MISSION THERAPEUTICS LIMITED (GB) | 2020-06-23 | — | — | US | disclosed |
| US-5780490-A | A O-(2,4-OXA(OR THIA)ZOLIDINYL)PHENYLOXY(OR THIO OR AMINO) ALKYLOXIME; ALDOSE REDUCTASE INHIBITORS; ANTIDIABETIC AND -HYPOGLYCEMIC AGENTS; LIVER, SKIN AND UROGENITAL DISORDERS | SANKYO COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |
| US-5756650-A | COMPOSITION COMPRISING POLYAMIC ACID, CURE ACCELERATOR SELECTED FROM GROUP CONSISTING OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, AMINO ACID COMPOUND, AROMATIC COMPOUND HAVING TWO OR MORE HYDROXYL GROUPS | KABUSHIKI KAISHA TOSHIBA (JP) | 1998-05-26 | — | — | US | disclosed |
| US-5703096-A | ANTIDIABETIC AGENTS; ALDOSE REDUCTASE INHIBITOR | SANKYO COMPANY, LIMITED (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |
| EP-0271798-B1 | O-SUBSTITUTED TETRAHYDROPYRIDINE OXIME CHOLINERGIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1993-04-07 | — | — | EP | disclosed |
| US-4786648-A | ANALGESIC | WARNER-LAMBERT COMPANY (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0271798-A2 | O-Substituted tetrahydropyridine oxime cholinergic agents | WARNER-LAMBERT COMPANY (US) | 1988-06-22 | — | — | EP | disclosed |
| US-4675044-A | DEFOLIANTS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1987-06-23 | — | — | US | disclosed |
| US-4569690-A | HERBICIDES, FUNGICIDES, PLANT DESSICANTS, DEFOLIANTS | UNIROYAL, INC. (US) | 1986-02-11 | — | — | US | disclosed |
| EP-0104940-A1 | 3-Aryl-5,6-dihydro-1,4,2-oxathiazines and their oxides | UNIROYAL, INC. (US) | 1984-04-04 | — | — | EP | disclosed |