Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27683902 | 0.79 | — | — | |
| SCHEMBL28756534 | 0.79 | CA1 (0.31) | — | |
| SCHEMBL27701793 | 0.78 | MEN1 (0.34) | LMNANOS3NOS1NOS2 | |
| SCHEMBL27759477 | 0.78 | CA12 (0.33) | — | |
| SCHEMBL27682688 | 0.78 | SRD5A1 (0.30) | — | |
| SCHEMBL27759470 | 0.78 | ESR1 (0.35) | — | |
| SCHEMBL29263232 | 0.76 | ALDH1A1 (0.35) | LMNASMN1; SMN2NSD2 | |
| SCHEMBL28844025 | 0.76 | — | — | |
| SCHEMBL29086898 | 0.76 | — | — | |
| SCHEMBL27860395 | 0.75 | RAB9A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101048388-A | Quinazolinone derivatives and their use as B-Raf inhibitors | ASTRAZENECA AB (SE) | 2007-10-03 | — | — | CN | disclosed |