Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27701807 | 0.83 | PLAU (0.44) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27722194 | 0.82 | TSPO (0.38) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27722213 | 0.82 | HDAC1 (0.52) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27722227 | 0.73 | NR1H4 (0.45) | PLAUHDAC1NR1H4MEN1KMT2A | |
| SCHEMBL27722270 | 0.72 | HDAC6 (0.39) | MAPTPLAUHDAC1MEN1KMT2A | |
| SCHEMBL27701659 | 0.72 | HDAC6 (0.37) | ALDH1A1MAPTPLAUHDAC1NR1H4 | |
| SCHEMBL28768873 | 0.71 | HDAC6 (0.38) | ALDH1A1PLAUHDAC1GAARAB9A | |
| SCHEMBL27722212 | 0.71 | PLAU (0.39) | ALDH1A1MAPTPLAUHDAC1GAA | |
| SCHEMBL27701823 | 0.71 | HDAC6 (0.38) | MAPTPLAUHDAC1MEN1KMT2A | |
| SCHEMBL27701646 | 0.71 | PLAU (0.39) | MAPTPLAUHDAC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163703-B | Imidazo [1,2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG | 2010-12-15 | — | — | CN | disclosed |
| CN-101163703-A | Imidazo [1, 2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG (CH) | 2008-04-16 | — | — | CN | disclosed |