Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 14/20 | 0.39 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.38 |
| ▸ | TP53 | P04637 | 9/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PKLR | P30613 | 5/20 | 0.35 |
| ▸ | PKM | P14618 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27722396 | 0.88 | KDM4E (0.33) | GAAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL22774397 | 0.80 | TP53 (0.55) | GAAMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL27722222 | 0.75 | ALDH1A1 (0.39) | GAAMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL27722332 | 0.75 | NR1H4 (0.41) | GAAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27722205 | 0.74 | ALDH1A1 (0.36) | GAAMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL27722391 | 0.73 | GAA (0.40) | GAAMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL27701637 | 0.72 | HDAC1 (0.42) | GAAMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL27722187 | 0.68 | GPR139 (0.38) | GAAMAPTKDM4EALDH1A1NPSR1 | |
| SCHEMBL27701664 | 0.67 | HTT (0.39) | GAAMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL27701766 | 0.66 | GRIN1 (0.34) | GAAMAPTKDM4EALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163703-B | Imidazo [1,2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG | 2010-12-15 | — | — | CN | disclosed |
| CN-101163703-A | Imidazo [1, 2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG (CH) | 2008-04-16 | — | — | CN | disclosed |